Altered States is a 1980 American science fiction-horror film adaptation of a novel by the same name by playwright and screenwriter Paddy Chayefsky. It was the only novel that Chayefsky ever wrote, as well as his final film. Both the novel and the film are based on John C. Lilly's sensory deprivation research conducted in isolation tanks under the influence of psychoactive drugs like ketamine and LSD. The film was directed by Ken Russell and featured William Hurt in his screen debut. It also featured Blair Brown (as Emily Jessup), Charles Haid and Bob Balaban. It additionally featured the film debut of Drew Barrymore. The film score was composed by classical composer John Corigliano (with Christopher Keene conducting) and was nominated for an Academy Award. The film also received an Oscar nomination for Sound, losing to The Empire Strikes Back. Edward Jessup (William Hurt) is a university professor of abnormal psychology who, while studying schizophrenia, begins to think that "our other states of consciousness are as real as our waking states.